Pre-Test Pulmonary Arterial Hypertension and Chronic Thromboembolic Pulmonary Hypertension in Primary Care: Updated Diagnostic Strategies and Treatment Options Pre-Test Which of the following statements about PAH is TRUE? At diagnosis, 50% of patients with PAH are classified with functional class I and II In PAH, vascular fibrosis develops in large arteries Risk factors for PAH include A and B blood types, certain cancers, and female sex PAH has been increasingly diagnosed in older patients in recent years Unsure European Society of Cardiology/European Respiratory Society guidelines released in October 2022 now define PAH as an elevation in resting mean pulmonary artery pressure (mPAP) ≥_____. 15 mm Hg 20 mm Hg 25 mm Hg 30 mm Hg Unsure Which of the following statements regarding the phase 3 STELLAR study is TRUE? The STELLAR trial showed that dual combination therapy of selexipag and tadalafil is efficacious in patients with inoperable CTEPH The STELLAR trial showed that monotherapy of sotatercept decreased morbidity and mortality by 36% in PAH compared to the control population The STELLAR trial showed that sotatercept added to currently approved background therapy showed a profound effect on improvement from baseline to 24 weeks in 6-minute walk distance The STELLAR trial showed that tri-therapy of ambrisentan, tadalafil, and sotatercept is not as efficacious as dual therapy in patients with PAH/CTEPH Unsure Stephanie , a 62-year-old woman, presents with worsening dyspnea on exertion and fatigue for several years. She was hospitalized a year and a half ago with shortness of breath. At that time, right heart catheterization showed mPAP of 54 mm Hg and normal wedge pressure; therefore, she was diagnosed with PAH. An ERA and anticoagulant were initiated. In the last 2 months, she developed palpitations and dizziness with exertion. Lung examination reveals posterior audible bilateral flow murmurs. She is 66 inches tall, weighs 148 pounds, BP is 110/65, heart rate is 76, and oxygen saturation is 94% on room air. What is the most likely diagnosis? CHD-associated PAH CTD-associated PAH CTEPH IPAH Unsure How confident are you in your ability to diagnose PAH and CTEPH in a timely fashion? Very confident Confident Somewhat confident Not very confident Not at all confident
